Everybody’s looking for the best and safest way to lose weight fast. Fad diets and diet pills could get the job done, but for long-term weight loss maintenance and overall health, we need to look much deeper – into our cells.

We are bombarded every single day with toxicity stemming from poor food choices, lifestyle, chemicals in our home, and chronic medication. While our body has a natural ability to detox/cleanse from exotoxins, it wasn’t designed to nor can it handle this daily burden.

It’s in this context that in 2005, with the help of some integrative medicine doctors, the 21 Day Full Body Cleanse system was made. It was designed to remove harmful toxins from cells and assist all the body’s organs and glands to work at their optimal levels. Since the WHO (World Health Organization) has recently revealed that about 7 million people die due to air pollution, we thought it prompt to review a product that will help protect us from this risk.

Readers please note that statements on this page are fair comment based on observation. This content is produced on a matter of public interest. Statements on this page are our honest opinion, not fact.

Let’s take a look at the top level pros and cons of this product:

21 Day Cleanse Benefits:

  • Could improve digestion reduce bloating
  • Can boost energy levels
  • May reduce hunger cravings
  • Strong antioxidant functions that support the immune system, liver and kidney functions
  • Balances total cholesterol, LDL and HDL, and triglycerides
  • Can contribute towards weight loss

21 Day Cleanse Drawbacks:

  • Not suitable for everyone
  • Some potentially negative side effects

21 Day Cleanse Product Image

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Some Quick Information About 21 Day Cleanse

The Full Body Cleanse is the original product of 21 Day Body Makeover, a program by George DiGianni. He trained celebrities, professional athletes, and business people like Mark Cuban, Michael Dell, and Eli Young. He’s hosted a radio show for 22 years and has a total of 30 years experience in the health and fitness industry

The 21 Day Cleanse system costs $197. This includes 30 days’ worth of supplements, 10 exercise videos made by George, meal recipes, health and wellness e-books written by George DiGianni, and access to support from experts for the duration of the program.

This detox cleanse system is designed to address all aspects of being healthy. This includes physical, mental, and emotional well-being. The ingredients used are natural, organic, and largely plant-based, but some contain soy, which is a common allergen. The formulations are backed by scientific research to make sure that ingredients are in the correct ratios for maximum efficacy.

The 21 Day Full Body Cleanse system aims to rid a person’s body of harmful toxins. You can get these from the environment (polluted air, water, stress-induced) as well as food (junk food, high fructose). It also makes sure that the person undergoing the program does not starve at any point, since starving will make the body hold on to fats longer.

Does 21 Day Cleanse Work?

Based on the website, the 21 Day Cleanse is made for people who want to lose weight and improve their overall health. This isn’t for people who are looking for a quick-and-dirty weight loss program. The 21 Day Cleanse approaches weight loss holistically, packing together potent supplements, healthy eating and exercise habits, and mental and emotional conditioning within the program.

The recommended dose is taking two (2) capsules of the capsule supplements and 2 scoops of the shake mixed with water or nut milk. Some of the 21 Day Cleanse supplements make use of phytosomes – a form that enables herbal extracts and other elements with low bioavailability to be easily absorbed by the cells. This ensures that takers of the 21 Day Cleanse supplements will enjoy the optimum efficacy of beneficial elements contained within each capsule. The supplements last 30 days and you will still have access to all exercise and recipe videos after you complete the Full Body Cleanse program.

The 21 Day Cleanse includes supplements that aid and boost the function of your body’s natural detox system – your liver, kidneys, and digestive organs. They work together to cleanse toxins out of your cells while infusing essential vitamins and minerals in your body.

There’s also a thermogenic component that aids weight loss. This thermogenic element helps you burn fat even while at rest. And since this program includes exercise videos you can follow as well as healthy meal plans, people doing the 21 Day Cleanse have experienced noticeable weight loss, better blood chemistry results, and improved overall feeling.

What Are The 21 Day Cleanse Ingredients?

The 21 Day Cleanse program includes the following supplements:


One Serving Contains: Pancreatin (140mg), Pepsin (70mg), Ox Bile concentrate (80mg), L-Glutamic Acid Hydrochloride (480mg), Betaine Hydrochloride (480mg), Leucine, Hypromellose capsule, Silicon Dioxide.

Green Tea Phytosome

One Serving Contains: Camellia sinensis extract (leaf) / Phosphatidylcholine complex (250mg), High and low viscosity hydroxypropyl methylcellulose and CalciumCitrateLaurate, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide

Liver Cleanse

One Serving Contains: Proprietary Blend (430mg), Dandelion extract, Burdock root extract, Berberine HCl, Milk Thistle fruit extract (Silybum marianum), Uva-ursi leaf extract, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide, Taraxacum PE 4:1, Arctium PE 4:1, Berberis Concentrate Berberine HCl 85%, Silybum standardized to Silymarin 65%, Actostaphylos PE 4:1

Medi Clear SGS

One Serving Contains: Vitamin A (1.5mg), Vitamin C (300mg), Vitamin D (10mcg), Vitamin E (80.6mg), Thiamin (12mg), Riboflavin (5mg), Niacin (38mg), Vitamin B6 (10mg), Folate (300mcg), Vitamin B12 (50mcg), Biotin (150mcg), Pantothenic Acid (50mg), Calcium (300mg), Iron (7mg), Magnesium (150mg), Zinc (10mg), Selenium (70mcg), Manganese (1.5mg), Chromium (100mcg), Molybdenum (50mcg), Sodium (360mg), Potassium (100mg), Proprietary Blend (26g), Pea Protein Isolate, Rice Protein , Glycine (1.65g), Medium Chain Triglycerides (1.5g), L-Glutamine (500mg), L-Lysine (500mg), Curcumin Phytosome (400mg), Milk Thistle Extract (250mg), Taurine (110mg), Methyl Sulfonyl Methane (100mg), Grapeseed Phytosome (50mg), Green Tea Phytosome (50mg), Betaine Anhydrous (50mg), N-Acetyl-L-Cysteine (50mg), Choline Citrate (30mg), Sulforaphane Glucosinolate (30mg), Glutathione (25mg), Boron (100mcg), Lutein (60mcg), Vanadium (50mcg), Cocoa, Flavors, Evaporated Cane Juice Sugar, Glucose, Stevia extract, Silicon Dioxide, Monk Fruit concentrate.

What Are The 21 Day Cleanse Side Effects?

We’ve compiled the following potential side effects based on the ingredients inside this formula:

Note: these side effects are possible but may not be the typical user experience.

Is 21 Day Cleanse Safe?

Looking at the ingredients of each individual supplement included in the 21 Day Cleanse program as well as the clear instructions on the right dosage and who can and cannot take them, we believe that the 21 Day Cleanse is safe to use. Most of the components used natural plant extracts, digestive enzymes, and vitamins and minerals.

What Claims Are Being Made About 21 Day Cleanse?

We have found the following claims and/or implications being made about this supplement:

    1. Weight loss
    2. Decrease in clothing size
    3. Lower blood pressure
    4. Improves sleep and energy
    5. Better eating habits and choices
    6. Eliminates cravings for sugar, caffeine, alcohol, etc.

Are There Any Reviews From Customers?

We have found the following 21 Day Cleanse review testimonials via customers online:

Since using the 21 day body makeover I have of energy all day, I sleep all night and recovered fast from surgery and I lost 4 pounds I feel great. If you are tired of feeling tired or need to shed pounds, order the 21 day body makeover today.

I used 21 day full body cleanse more than once. The first time, I lost 18 pounds and I also completely broke my addiction to diet sodas. My skin cleared up and I slept great and I was well-rested every morning and I had no cravings for sugar at all. The program was so easy to follow and I never felt hungry. I can even dine in restaurants whenever I want it and the best news of all is that I have kept all the weight off.

These testimonials are sourced from the official 21 Day Body Makeover Website and as such should be taken with bias in consideration.

Where Can I Buy This Product?

You can buy the 21 Day Cleanse system on the official 21 Day Body Makeover website.

Our Conclusion.

According to studies, as the body becomes cleansed, it can then absorb essential nutrients better. With this in mind, we believe that the 21 Day Cleanse is a worthwhile product that uses top-quality ingredients and designed by a former celebrity trainer with extensive health and fitness experience. The program itself gives more value in the way that it’s carefully designed to address the root problems of weight gain. It takes into account all the aspects of being healthy. We like how this is an organic full body cleanse, which means everything you need is all here.

If you’re someone who has a lot of bad eating habits and living a sedentary lifestyle, this program is a great jump-off point for building good and healthy habits towards sustaining weight loss and overall good health.

Kath Ross, PhD
Kath Ross, PhD
Health Editor at DietProbe
Kathryn is a Ph.D Health Editor here at DietProbe. She specializes in diabetes and weight control research and in her spare time she's a professional cat lady and wine connoisseur!
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