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Introduction

Have Nugenix created something revolutionary with this estrogen blocker? They claim it can be used to help maximize the results delivered from their free testosterone booster supplement, but as always, we are skeptical.

In this Nugenix Estro Regulator review, we’re taking an in-depth look into the formula to establish what it truly is capable of.

Readers please note that statements on this page are fair comment based on observation. This content is produced on a matter of public interest. Statements on this page are our honest opinion.

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What Is Nugenix Estro Regulator?

Nugenix Estro Regulator is a natural estrogen blocker supplement created by a US-based nutrition brand named Nugenix.

One bottle of Estro Regulator costs $49.99, contains 60 capsules and will last users for exactly one month, based on the directions of 2 capsules per day; it is available from the official Nugenix Estro Regulator website, GNC and Amazon.

This product is designed to be used in conjunction with their free testosterone booster supplement, and is designed to help support those looking to gain muscle mass.

The product itself is a complex of vitamin E, with added herbal extracts. Nugenix officially state that the product contains natural “anti-aromatase modulators”, going on to claim that it helps to prevent testosterone from being converted into estrogen.

Does Nugenix Estro Regulator Work?

A supplement is only as good as the sum of its parts; when investigating this product we looked to see whether or not it actually contained ingredients useful for inhibiting estrogen. After some further research, we believe that it could have mild benefits.

The main ingredient inside this product is Diindolylmethane, more commonly referred to as DIM. Clinical research conducted in 2011 showed that DIM can help modulate estrogen metabolism. Another study conducted a year later showed that the substance indeed had anti-estrogen properties.

Other ingredients such as Polygonum Cuspidatum and Chrysin unfortunately do not have any solid research showing they’re truly effective for inhibiting Aromatase.

The Pros & Cons Of Nugenix Estro Regulator

Below we’ve made a complete list of everything that we like and dislike about this estrogen blocker:

The Pros

  • May help contribute towards the metabolism of Estrogen.

The Cons

  • The effect-intensity of this product is unlikely to have any major impact on the user’s free testosterone levels.
  • Very expensive.
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What Are The Nugenix Estro Regulator Ingredients?

We have found the following supplement facts for this product:

One Serving Contains: Vitamin E 10IU, Chrysin 500mg, Polygonum Cuspidatum Extract 300 mg, and Diindolylmethane (DIM) 100mg.

Is Nugenix Estro Regulator Safe?

We believe that this product is very safe, provided you stick to the directions of usage. The formula is free from any banned or illicit substances.

What Are The Nugenix Estro Regulator Side Effects?

We’ve compiled the following potential side effects based on the ingredients inside this formula:

  • Could potentially worsen conditions such as cancer
  • Might slow blood clotting [1][2][3]

Note: these side effects are possible but may not be the typical user experience.

Are There Any Nugenix Estro Regulator Reviews From Customers?

We have found the following Nugenix Estro Regulator review testimonials via customers online:

I know what this product is suppose to do. When I started it with my other Nugenix product, it felt like my energy level dropped. When I stopped, my energy levels climbed back up. I’m disappointed that it had that affect on me. Like I said, I know what it’s supposed to do and I was hoping to get rid of this estrogen titty fat.

I tried Nugenix Estrogen Regulator in tandem with Nugenix Testosterone Booster. This product made no noticeable difference in my health or well being.

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Our Final Verdict On Nugenix Estro Regulator

To conclude our Nugenix Estro Regulator review, there are good things about the product and there are some downsides to it as well.

Starting with the positives, we like how this product contains DIM, a natural substance that has certain studies showing that it really can help metabolize estrogen to a certain extent.

The negatives are, the rest of the ingredients don’t have too much scientific backing and likely won’t do much. We’re also skeptical if this product will reduce estrogen enough to promote any sort of “test boosting” effects – further clinical testing would be required.

Kath Ross, PhD
Kath Ross, PhD
Health Editor & Fact Checker at DietProbe
Kathryn is a Ph.D Health Editor here at DietProbe. She specializes in diabetes and weight control research and in her spare time she's a professional cat lady and wine connoisseur!
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Fact Checked


This article has been reviewed and fact-checked by a certified nutritionist, and only uses information from credible academic sources.